How to take

During your first week, you’ll take the starter dose (231 mg) as one pill twice a day.

After your first week, you’ll take the regular dose (462 mg) as two pills twice a day. It's important to take VUMERITY® (diroximel fumarate) exactly as prescribed by your
healthcare provider.

Swallow VUMERITY whole. Do not crush, chew, or sprinkle contents on food.

If you take too much VUMERITY, call your healthcare provider or go to the nearest hospital emergency room
right away.

Dosage Options VUMERITY Starter dose VUMERITY Regular dose
(DAYS 1-7)

1 pill (231 mg) twice a
day for your first week


2 pills (462 mg)
twice a day

What should you know about food?

If you take VUMERITY with food, avoid taking with a high-fat, high-calorie meal or snack.
  • Your meal or snack should contain no more than 700 calories and no more than 30 grams of fat

Here are two examples that follow these guidelines:

  • 1 whole wheat English muffin 
  • 2 tablespoons peanut butter 
  • 1 small hard-boiled egg
  • 1 medium banana
  • 8 ounces 2% reduced-fat milk
  • 4 ounces grilled skinless chicken breast
  • 1 cup cooked white rice
  • 1 cup cooked and salted broccoli
  • 1 tablespoon salted butter
  • 1/2 cup vanilla ice cream
What should I avoid while taking VUMERITY?
  • Do not drink alcohol at the same time you take your VUMERITY dose

Helpful information on taking VUMERITY

Sticking to a regular schedule may help you remember to take it twice a day.

Fork knife plate

If you take two pills with breakfast and two pills with dinner, it could help you remember to take VUMERITY twice a day.


Store VUMERITY at room temperature between 68°F and 77°F.


Use the myVUMERITY™ app to be reminded of your daily doses.

Taking VUMERITY exactly as prescribed by your healthcare provider gives you the best chance of getting its full benefits.