VUMERITY Serious
side effects

Understanding potential serious side effects

Are you and your healthcare provider considering VUMERITY® (diroximel fumarate)? If so, there are a few important topics to discuss, such as serious side effects.

It's important to tell your healthcare provider if you experience an allergic reaction to VUMERITY or any of its ingredients.

Before taking VUMERITY, it's also important to talk with your healthcare provider about the potential serious side effects associated with it. Serious side effects of VUMERITY include:

Allergic reactions

Allergic reactions (such as welts, hives, swelling of the face, lips, mouth or tongue, or difficulty breathing).

PML

PML is a rare brain infection that usually leads to death or severe disability over a period of weeks or months. Tell your healthcare provider right away if you get any of these symptoms of PML:

  • weakness on one side of the body that gets worse
  • clumsiness in your arms or legs
  • vision problems
  • changes in thinking and memory
  • confusion
  • personality changes
Herpes zoster infections (shingles)

Herpes zoster infections (commonly known as shingles), including infections of the central nervous system.

Decreases in your white blood
cell count

Your healthcare provider should check your white blood cell count before you start VUMERITY, 6 months after starting treatment, and then every 6-12 months thereafter as they feel necessary.

Liver problems

Your healthcare provider should do blood tests to check your liver function before you start taking VUMERITY and during treatment if needed. Tell your healthcare provider right away if you get any symptoms of a liver problem during treatment, including:

  • severe tiredness
  • loss of appetite
  • pain on the right side of your stomach
  • dark or brown (tea color) urine
  • yellowing of your skin or the white part of your eyes

Your healthcare provider should do a blood test before you start treatment with VUMERITY and while you’re on therapy.

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